The Wake Forest University School of Medicine and Atrium Health team has secured a $2. 5 million funding award from the Patient-Centered Outcomes Research Institute (PCORI) to enhance antibiotic prescribing for children with acute respiratory tract infections in outpatient settings. The project will be led by Jennifer Sullivan, M. D. , M. P. H. , and co-lead by Lisa Davidson, M. D. , aiming to address the risks associated with inappropriate antibiotic prescribing for pediatric patients. The Atrium Health Children’s Optimal Outpatient Stewardship (AH-CHOOS) program will focus on implementing research findings that narrow-spectrum antibiotics are as effective as broad-spectrum ones, with fewer side effects for treating acute respiratory tract infections in children. The initiative will expand across multiple sites served by Atrium Health and engage over 2,000 healthcare providers in enhancing appropriate antibiotic prescribing practices through education, data reporting, and evidence-based interventions. The ultimate goal is to prevent drug-resistant infections and reduce adverse side effects by empowering providers to use antibiotics judiciously and engage patients and caregivers in their care.